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Lipoma and Homoeopathy

© Dr. Rajneesh Kumar Sharma M.D. (Homoeopathy)

Dr. Deepika Vishwakarma BHMS

Dr. Manoj Singh Chauhan D Pharm, BHMS

Homoeo Cure & Research Institute

NH 74, Moradabad Road, Kashipur (Uttaranchal) INDIA

Pin- 244713 Ph. 05947- 260327, 9897618594

  1. mail- drrajneeshhom@hotmail.com

                    www.treatmenthomeopathy.com

                    www.cureme.org.in

For well formatted and illustrated article, please see attached file...

Lipoma and Homoeopathy.pdf

Definition. 2

Incidence. 2

Causes. 2

Signs and symptoms. 2

Pathophysiology. 3

Types. 3

According to histology. 3

Based on number. 4

Based on origin. 4

Based on site. 5

Lipomatosis. 5

Diagnosis. 5

Differential diagnosis. 6

Madelung's disease. 6

Diffuse lipomatosis. 6

Dercum's disease (adiposis dolorosa) 6

Encephalocraniocutaneous lipomatosis. 6

Proteus syndrome-multiple lipomas. 6

Bannayan-Riley-Ruvalcaba syndrome. 6

Cowden syndrome. 6

Multiple endocrine neoplasia type 1. 6

Frohlich syndrome. 6

Gardner syndrome. 6

Liposarcoma. 6

Complications. 6

Treatment. 7

Homoeopathic treatment. 7

Bibliography. 9

Definition

Lipoma is a common benign adipose tumor with uniform nuclei, which is usually painless, soft, rubbery, easily movable and often located in the subcutaneous tissues of the head, neck, shoulders, and back, appearing single or multiple. (Psora/ Sycosis)

Incidence

  • Most common soft tissue tumor
  • Adults above 40 years
  • Both sexes
  • Rare in children
  • Associated with obesity
  • Multiple lipomas 5%, more common in women, often familial, associated with neurofibromatosis, multiple endocrine neoplasia syndromes, Bannayan syndrome (macrocephaly, hemangiomas and lipomas)

Causes

The cause of lipomas is unknown. There may be genetic involvement as many patients with lipomas come from a family with a history of these tumors (Psora/ Sycosis). Sometimes an injury may trigger growth of post-traumatic lipomas (Causa occasionalis).

Signs and symptoms   

It is often difficult to appreciate presence of lipomas until they have grown large enough to become visible and palpable (Psora/ Sycosis). Growth occurs slowly over several years. Their characteristics are-

  • Relatively static growth after initial growth period (Psora)
  • Does not regress even with starvation (Psora)
  • Becomes hard after application of ice (Psora)
  • A dome-shaped or egg-shaped lump about 2-10 cm in diameter or even larger (Psora/ Sycosis)
  • Feels soft and smooth and easily movable under the skin (Psora)
  • May have a rubbery or doughy consistency (Psora/ Sycosis)
  • Multiple lipomas may occur in groups of two to hundreds of confluent painless tumors of various sizes over any part of the body
  • Lipoma sites are-
    • Usually trunk, back, shoulder, neck, proximal extremities
    • Rare on hands, feet, face, lower leg, retroperitoneum
    • Usually subcutaneous (liposarcomas are usually deep seated)
    • Unusual sites include oral cavity, pancreas, breast, intestines
    • Less common in internal organs

Most lipomas are symptomless, but some are painful on applying pressure. Tender or painful lipomas are usually angiolipomas, lipoma with increased number of small blood vessels. Painful lipomas are also a feature of adiposis dolorosa or Dercum disease.

Pathophysiology

  • Simple lipomas are circumscribed encapsulated soft masses, made up of fat mainly (Psora)
  • Occasionally solid components are also present like blood vessels, muscle fibers, fibrous septae, and fat necrosis (Psora/ Sycosis/ Syphilis)
  • Histology demonstrates mature adipocytes with no cellular atypia or pleomorphism (Psora)
  • Lipomas differ biochemically from normal fat by demonstrating increased levels of lipoprotein lipase and the presence of a large number of precursor cells (Psora/ Sycosis)
  • Approximately 60% of solitary cutaneous lipomas display clonal alterations. The most common alteration involves a breakpoint on bands 12q13-15 (Psora)
  • Karyotype aberrations also have been noted on arms 6p and 13q. Multiple lipomas do not display these alterations. (Psora)

Types

There may be several types of lipomae based on their morphology, histology, origin, site and number.

According to histology

Conventional lipoma

Common, mature white fat, also called encapsulated subcutaneous lipoma.

Hibernoma

Brown fat instead of the usual white fat

Fibrolipoma

Fat plus fibrous tissue

Angiolipoma

Fat plus a large amount of blood vessels, painful subcutaneous nodules having all other features of a typical lipoma.

Myelolipoma

Fat plus tissue that makes blood cells

Angiolipoleiomyoma

Acquired, solitary, asymptomatic acral nodules, characterized histologically by well-circumscribed subcutaneous tumors composed of smooth muscle cells, blood vessels, connective tissue, and fat.

Pleomorphic lipoma

Like spindle-cell lipomas, occur for the most part on the backs and necks of elderly men and are characterized by floret giant cells with overlapping nuclei.

Spindle-cell lipoma

Asymptomatic, slow-growing subcutaneous tumors that have a predilection for the posterior back, neck, and shoulders of older men.

Based on number

Solitary lipoma

Solitary encapsulated lipoma

Multiple lipomas

Dercum’s disease

Based on origin

Neurolipoma

Lipomas associated with nerves.

Naevolipoma

Lipomas associated with naevi.

Adenolipomas

Lipomas associated with eccrine sweat glands.

Based on site

Cerebellar pontine angle and internal auditory canal lipomas

Located at cerebellar pontine angle and internal auditory canal lipomas.

Chondroid lipomas

Deep-seated, firm, yellow tumors that characteristically occur on the legs of women.

Corpus callosum lipoma

A rare congenital brain condition that may or may not present with symptoms. This occurs in the corpus callosum, also known as the calossal commissure, which is a wide, flat bundle of neural fibers beneath the cortex in the human brain.

Intradermal spindle cell lipoma

Distinct in that they most commonly affect women and have a wide distribution, occurring with relatively equal frequency on the head and neck, trunk, and upper and lower extremities.

Neural fibrolipoma

Overgrowths of fibro-fatty tissue along a nerve trunk, which often leads to nerve compression.

Lipomatosis

An autosomal dominant condition in which multiple lipomas are present on the body. Many discrete, encapsulated lipomas form on the trunk and extremities, with relatively few on the head and shoulders.

Familial multiple lipomatosis

Familial multiple lipomatosis (FML) is a rare condition that is characterized by multiple lipomas on the trunk and extremities. As the name suggests, FML is diagnosed when multiple lipomatosis occurs in more than one family member, often over several generations.

‎Multiple symmetric lipomatosis

Multiple symmetric lipomatosis is a rare condition characterized by the symmetric growth of fatty tumors (lipomas) around the neck, shoulders, upper arms and/or upper trunk. It most often affects men of Mediterranean ancestry between the ages of 30 and 70 who have a history of alcohol abuse.

‎Familial multiple lipomatosis

Familial multiple lipomatosis (FML) is a hereditary syndrome of multiple encapsulated lipomas which are found on the trunk and extremities, with relative sparing of the head and shoulders.

Diagnosis

  • Clinically by finding a soft lump under the skin
  • Deep skin biopsy

Differential diagnosis

Madelung's disease

Benign symmetric lipomatosis or multiple symmetric lipomatosis.

Diffuse lipomatosis

Characterized by an early age of onset, usually before the age of 2, diffuse infiltration of muscle by an un-encapsulated mass of histologically mature lipocytes and progressive enlargement and extension of the tumor mass. It usually involves a large portion of the trunk or an extremity.

Dercum's disease (adiposis dolorosa)

Seen most often in obese or corpulent menopausal women who develop symmetrical, tender, circumscribed fatty lesions. They are often accompanied by weakness and psychiatric disturbances.

Encephalocraniocutaneous lipomatosis

A rare neurocutaneous syndrome characterized by unilateral porencephalic cysts with cortical atrophy, ipsilateral facial and scalp lesions, ocular abnormalities, cranial asymmetry, and neurologic complications.

Proteus syndrome-multiple lipomas

Epidermal nevi, cerebriform lesions of the plantar surfaces, vascular malformations, macrodactyly, hemihypertrophy, exostoses, and scoliosis.

Bannayan-Riley-Ruvalcaba syndrome

Characterized by multiple subcutaneous lipomas and vascular malformations, lentigines of the penis and vulva, verrucae, and acanthosis nigricans.

Cowden syndrome

Characterized by multiple benign tumor like growths called hematomas and increased risk of developing malignancy.

Multiple endocrine neoplasia type 1

Skin lesions consisting of multiple facial angiofibromas, collagenomas, cafi-an-lait spots, lipomas, confetti-like hypopigmented macules, and multiple gingival papules in addition to the tumors of the parathyroid glands, endocrine pancreas, and anterior pituitary.

Frohlich syndrome

Consists of multiple lipomas, obesity, and sexual infantilism.

Gardner syndrome

Consists of multiple osteomas, fibromas, desmoid tumors, lipomas, fibrosarcomas, epidermal inclusion cysts, and leiomyomas, associated with intestinal polyposis exclusively in the colon and rectum.

Liposarcoma

A cancer that arises in fat cells in deep soft tissue, such as that inside the thigh or in the retroperitoneum.

Complications

  • Myxomatous degeneration
  • Saponification
  • Calcification
  • Infection
  • Ulceration
  • Intussusception
  • Intestinal obstruction

Treatment

Most lipomas require no treatment. Most lipomas eventually stop growing and remain indefinitely without causing any problems. To eliminate patient’s anxiety for lipoma, it may be removed. If small, the lesions may be ignored, otherwise it may be removed completely by surgery.

Occasionally, lipomas that interfere with the movement of adjacent muscles may require surgical removal.

Lipoma of the lumber region may be associated with spina bifida occulta and removal of the tumor is dangerous without simultaneous exploration of the cauda equina.

Simple surgical excision, squeeze technique (a small incision is made over the lipoma and the fatty tissue is squeezed through the hole) and liposuction may be adopted.

Homoeopathic treatment

Homoeopathic remedies do miracles with disappearance of lipoma if applied as per rules on similia. The most effective remedies are- agar. AM-M. aur. bacls-10. BAR-C. BELL. calc-ar. CALC. Croc. cypr. graph. guare. KALI-BR. LAP-A. med. merc. petr. Phos. PHYT. sil. Spong. Sulph. Thuj. ur-ac.

Short repertory of Lipoma

CHEST - TUMORS - lipoma, false ribs - left, non-malignant carc.

CHEST - TUMORS - lipoma, false ribs bacls-10. carc.

CHEST - TUMORS - Lipoma, lower ribs - left side, non-malignant carc.

CHEST - TUMORS - Lipoma, lower ribs bacls-10. carc.

Clinical - tumors, general - fatty, tumors am-m. bar-c. calc. lap-a.

Clinical - tumors, general - head, tumors – lipoma croc.

Clinical - tumors, general - lipoma, fatty, tumors - liquors, from abuse of Calc.

Clinical - tumors, general - lipoma, fatty, tumors - neck, on Bar-c. Phos.

Clinical - tumors, general - lipoma, fatty, tumors - scalp, on Croc.

Clinical - tumors, general - lipoma, fatty, tumors – scrofulous Calc.

Clinical - tumors, general - lipoma, fatty, tumors agar. Am-m. Bar-c. Bell. calc-ar. Calc. croc. graph. Kali-br. Lap-a. phos. Phyt. Thuj. ur-ac.

Clinical - tumors, general - neck, lipomas, fatty, on  Bar-c. calc. Thuj.

Clinical - tumors, general - neck, lipomas, fatty, on - cystic, on both sides brom.

Clinical - tumors, general - neck, lipomas, fatty, on - malignant on calc-p.

EXTERNAL THROAT - WARTS - tough, like lipoma and pointed thuj.

EXTREMITIES - LIPOMA – Thighs bar-c. petr.

EXTREMITIES – LIPOMA petr.

FACE - TUMORS - lipoma, nose - alcohol, from abuse of ars. bell. calc. hep. merc. nux-v. puls. sulph.

FACE - TUMORS - lipoma, nose - contusion, from arn. con. rhus-t.

FACE - TUMORS - lipoma, nose - mercury, from abuse of aur. bell. hep. sulph.

FACE - TUMORS - lipoma, nose – scrofulous aur. bry. calc. hep. lach. merc. phos. puls. sulph.

FACE - TUMORS - lipoma, nose arn. ars. aur. bell. bry. calc. con. hep. lach. merc. nux-v. phos. puls. rhus-t. SULPH.

Fevers - HECTIC, fever - lipoma, on neck Phos.

GENERALITIES - Tumors – Lipoma Bar-c. calc-ar. calc. lap-a. phyt. Thuj. ur-ac.

GENERALITIES - TUMORS, benign – lipoma agar. Am-m. aur. bacls-10. BAR-C. BELL. calc-ar. Calc. carc. croc. cypr. graph. Kali-br. Lap-a. med. phos. Phyt. Thuj. ur-ac.

Growths new, tumours etc – lipoma aur. croc. lap-a. phos. phyt.

HEAD - TUMORS – lipoma croc.

Neck - TUMORS, lipomas, fatty, on neck - cystic, on both sides brom.

Neck - TUMORS, lipomas, fatty, on neck - malignant, on calc-p.

NOSE - LIPOMA - alcohol, from abuse of ars. bell. calc. hep. merc. nux-v. puls. sulph.

NOSE - LIPOMA - contusion, from arn. con. rhus-t.

NOSE - LIPOMA - mercury, from abuse of aur. bell. hep. sulph.

NOSE - LIPOMA – scrofulous aur. bry. calc. hep. lach. merc. phos. puls. sulph.

NOSE – LIPOMA arn. ars. aur. bell. bry. calc. con. hep. lach. merc. nux-v. phos. puls. rhus-t. Sulph.

NOSE – LIPOMA Sulph.

Nose - LIPOMA, nose arn. ars. aur. bell. bry. calc. con. hep. lach. lap-a. merc. nux-v. phos. puls. rhus-t. Sulph.

SKIN - TUMORS – lipoma beryl.

Bibliography

 BENIGN NEOPLASMS AND HYPERPLASIAS > LIPOMA ICD-10: D17.910 Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology, 8e... Figure 9-47 Lipoma (A) Well-defined, soft, rounded tumors in the subcutis, movable both against the overlying skin and the underlying structures, in a 56-year-old male patient. In this patient, lesions were symmetric and were also found on the trunk and upper extremities. (B) Solitary...

 Benign Tumors and Vascular Lesions > LIPOMA Clinical Dermatology

 Cardiac Tumors > 3. Lipoma: An encapsulated adipose cell tumor of cardiac chambers. CURRENT Diagnosis & Treatment: Cardiology, 5e... Figure 32–4. Transesophageal echocardiogram in the mid-esophageal view showing a dumbbell-shaped mass, consistent with lipomatous hypertrophy of the interatrial septum ( arrows ). a . D emographics —Lipomas also account for about 8% of cardiac tumors, their incidence being...

 Chapter 27. Neck Masses > Lipomas CURRENT Diagnosis & Treatment in Otolaryngology—Head & Neck Surgery, 3e... Lipomas occur most frequently in patients over 35 years of age. They are ill-defined soft masses that can occur in various neck locations. Lipomas are asymptomatic and can be diagnosed on CT scans as having fat-air density or by their bright appearance on T1-weighted MRI. The treatment is surgical...

 Chapter 28. Neck Neoplasms & Neck Dissection > Lipomas CURRENT Diagnosis & Treatment in Otolaryngology—Head & Neck Surgery, 3e... Lipomas are the most common benign soft-tissue neoplasms. They arise from the subcutaneous tissue and present as painless, smooth, encapsulated, and round masses. Fifteen to twenty percent of all lipomas occur in the head and neck. Most of these neoplasms are solitary lesions and are easily...

 Chapter 39. Benign Disorders of the Vulva & Vagina > Leiomyoma, Fibroma, & Lipoma CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e... of fibroblasts, vary in size from small subcutaneous nodules revealed incidentally to large polypoid tumors. Large tumors often undergo myxomatous degeneration and are very soft and cystic to palpation. Lipomas consist of a combination of mature fat cells and connective tissue. They can be differentiated from...

 Chapter 46. Diseases of the Peripheral Nerves > Multiple Symmetrical Lipomas With Sensorimotor Polyneuropathy Adams & Victor's Principles of Neurology, 10e... Whereas the usual cutaneous lipomas have no neurologic accompaniments, this clinical curiosity, known as Launois-Bensaude disease, consists of symmetrical lipomas of the neck and shoulders that are associated with polyneuropathy and sometimes, deafness. A mitochondrial disorder of similar genetic...

 Chapter 5. Cardiac Computed Tomography > Lipoma Multimodal Cardiovascular Imaging: Principles and Clinical Applications... Lipomas typically occur in adults, although they can also be seen in children. They generally occur as solitary masses that can arise from the epicardial surface spreading into the pericardial space 73 or from the interatrial septum or endocardial surface as a broad base from which they can...

 Chapter 5. Musculoskeletal Oncology > Lipomas Current Diagnosis & Treatment in Orthopedics, 5e... The lipoma is by far the most common soft-tissue tumor, accounting for approximately 50% of all soft-tissue tumors. Lipoma outnumbers liposarcoma by a ratio of 100:1. Cytogenetic abnormalities have been reported in 50–80% of lipomas. There are a large number of variants including the superficial...

 Chapter 62. Nonacoustic Lesions of the Cerebellopontine Angle > Lipomas CURRENT Diagnosis & Treatment in Otolaryngology—Head & Neck Surgery, 3e... Lipomas are rare lesions of the CPA and IAC. They are due to congenital malformations that lead to proliferation of adipocytes in subarachnoid cisterns or ventricles. MRI parallels the intensities of fat, and so lipomas are hyperintense on T1-weighted imaging, show no enhancement with gadolinium...

 Colon, Rectum, and Anus > Lipomas Schwartz's Principles of Surgery, 10e... Lipomas occur most commonly in the submucosa of the colon and rectum. They are benign lesions, but rarely may cause bleeding, obstruction, or intussusception, especially when greater than 2 cm in diameter. Small asymptomatic lesions do not require resection. Larger lipomas should be resected...

 Encyclopedia Homoeopathica

 Large Intestine > Lipomas CURRENT Diagnosis & Treatment: Surgery, 14e... The colon is the most frequent site of gastrointestinal lipomas. They are benign fatty submucosal tumors with an incidence of 1%-4%. They are more common in women and in the right colon. Lipomas are generally asymptomatic, however, they may cause vague abdominal symptoms or intussusception...

 Multiple Endocrine Neoplasia > Lipomas Harrison's Principles of Internal Medicine... Subcutaneous lipomas occur in >33% of patients with MEN 1 ( Table 408-1 ) and are frequently multiple. In addition, visceral, pleural, or retroperitoneal lipomas may occur in patients with MEN 1. Management is conservative. However, when surgically removed for cosmetic reasons...

 Radar 10

 Stomach > Lipoma Schwartz's Principles of Surgery, 10e... Lipomas are benign submucosal fatty tumors that are usually asymptomatic, found incidentally on upper GI series or EGD. Endoscopically, they have a characteristic appearance; there also is a characteristic appearance on EUS. Excision is unnecessary unless the patient is symptomatic. ...

 Surgery of the Hand and Wrist > Lipoma Schwartz's Principles of Surgery, 10e... Lipomas of the hand and wrist may occur in multiple anatomic locations, including subcutaneous tissues; intramuscularly (especially thenar or hypothenar muscles); deep spaces; carpal tunnel or Guyon’s canal; and rarely bone or nerve. They typically present as a painless, slow-growing, soft...

 The Head and Neck > Scalp mass—lipoma DeGowin’s Diagnostic Examination, 10e

 The Skin and Nails > Lipomas DeGowin’s Diagnostic Examination, 10e... Benign tumors of mature adipose tissue can arise in any area of adipose tissue. They are multiple and appear to be hereditary. Lipomas are common and occur mostly on the trunk and proximal extremities. They can be tender when they first appear or if they are traumatized. They are smooth...

 Thoracic Wall, Pleura, Mediastinum, & Lung > 1. Lipomas CURRENT Diagnosis & Treatment: Surgery, 14e... Lipomas are the most common benign tumors of the chest wall. Occasionally, they are very large and lobulated, and they may have dumbbell-shaped extensions that indent the endothoracic fascia beneath the sternum through an intercostal space. They may communicate with a large mediastinal...

 Upper Gastrointestinal Tract Cancers > Lipomas

 

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