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Pathogenesis of Acne

There are 4 basic factors involved in the development of acne.

Follicle Blockage

Acne arises due to blockage of follicles, the sebaceous follicles which are found in the face, neck, chest, and/or back. In acne patients, the sebaceous glands attached to these follicles secrete excessive amounts of sebum. It has been shown that the sebaceous glands in acne patients tend to be hyperresponsive to androgens, which are first released in the prepubertal period. Thus, these patients produce more sebum than is normal; this excessive secretion is a necessary prerequisite for the onset of acne.

Abnormal Desquamation

Second, the epithelial cells (keratinous squamous cells) lining of inner most layer of the follicles undergo abnormal desquamation. The cause why it happens is unknown. Normally, keratinous squamous cells are loosely organized in normal follicle, but they become denser and more coherent as a result of abnormal desquamation. The combination of abnormally desquamated cells and excessive sebum forms a “plug,” or microcomedo — the precursor lesion of both noninflammatory comedones and inflammatory lesions.


Third, the propionibacterium acne is a bacterium that lives on your skin and uses the sebum as nutrients for his growth. The sebaceous glands are hypersensitive to androgens that causes enlarge of gland and more sebum secretion. In puberty the androgens hormone is secreted more and thus there is more sebum secretion and more Propionibacterium acne in the follicle. The presence of P.acne attracts WBC to the follicle and thus an inflammatory reaction is settled up


Fourth, P acnes produces proinflammatory mediators and chemotactic factors that can cause microcomedones to inflame and evolve into papules, pustules, and nodules.

How Homeopathy Helps

  • A proper homeopathy treatment reduces the hypersensitivity of sebaceous gland to androgen hormone so helps to maintain a normal secretion of sebum. That prevents the acne formation.

  • Homeopathy remedies have anti inflammatory effect and accelerate the healing process in inflamed acne conditions.

  • Propionibacterium acnes is a frequent cause of bacterial keratitis and may cause propionibacterium acne keratitis. Homeopathy remedies treats successfully to the P.acne keratitis condition.

  • Homeopathy treatment controls the scar formation.

  • A constitutional homeopathy treatment not only treats the acne condition but also treats the whole patients as a whole.

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Comment by Dr.Rangadhar Satapathy.MD(Hom) on March 15, 2012 at 4:48am

Dear Dr.Singh

Yes you are absolutely right. The cause is the vital part for any treatment including Homeopathy. Looking after causative factors we can minimize the group of remedies. But the next step is same to go for totality of symptoms and I prefer and follow the Boeninhhausen's philosophy in all acute cases but in any chronic health issue both Kent and boeninghausen. 

Comment by Kuldip Singh on March 14, 2012 at 2:43pm


Dr. Satapathy,

You have done well in presenting a variety of causes for acne. Cause is an essential factor behind any form of treatment. So it is with homeopathy. I am sure you must be having a good experience in treating these forms of acne. Kindly share with us here, for the benefit of HWC members. Thanks.

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