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Mode of Action of Veratrum album in hypertension

Veratrum album is place in first grade in rubric Hypertension in repertories. Its potent antihypertensive efficacy and unusual mode of action are noteworthy. It alters the responsiveness of the vagal afferent nerve fibers in the coronary sinus, left ventricle, and carotid sinus so that any pressure stimulus will result in increased nerve traffic. This stimulus is interpreted in the medullary vasomotor centers as reflecting a higher pressure than actually exists as a result of an induced delay in the vagal repolarization process.

 

Hemodynamic Effects

As a result of this altered afferent input to the central vasomotor centers, there is a reflexive fall in systolic and diastolic pressure and heart rate; the latter response may be abolished by atropine sulfate. Because adrenergic function is not blocked, only reset at a different pressure level, the usual postural and adrenergic reflective responses are not altered. The result is a significant fall in total peripheral resistance with little change in cardiac output despite the rather marked bradycardia. Cerebral and renal blood flow and glomerular filtration rate remain normal unless the hypotensive response is excessive.

 

Symptomatogenesis

Because of the effective therapeutic affinity, the effective control of arterial pressure by the Veratrum is not infrequently associated with concomitants, including nausea, vomiting, excessive salivation and diaphoresis, blurred vision, and mental confusion, coldness, craving for icy cold drinks and lemonade and characteristically- cold perspiration on forehead.

 

Clinical Uses

Clinical use of the Veratrum album has been useful in the treatment of certain hypertensive emergencies, including eclampsia and pheochromocytoma (rare tumor of adrenal gland tissue) if symptomatology agrees.

 

 

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very nice information thank you sir

Good Sir

 

This is very interesting, as I am currently treating someone with Glonium 6x, 3 times daily in conjunction with their constitutional remedy for hypertension, and it dosen't seem to be working. I might try Veratrum album, but I was wondering if you could let me know what potency and how often you repeat eg. would you give in low dose daily in conjunction with constitutional remedy etc.

I am also currently treating someone with with opium in lm form, twice a day for diabetes mellitus. She was doing really well eg. able to think clearer in her head, energy levels up, uterine prolapse improved etc, but on lm 3 she got continual diarrheoa, with severe cramping, fowl smelling wind, and lose of appetite. I put her on lm 4 in the hope that it would stop her symptoms, but it only helped a little bit.

Therefore I put her on verab alb 30c dissolved in water as an acute to deal with her symptoms. It has helped a lot, but she is still not well, and she is taking the lm 4 once a day now. I was wondering if you have any suggestions eg. She I continue with the verab alb in water? Should I lessen the dose of opium lm to once a week ? should I antidote the opium (I really don't want to antidote as this remedy covers all her symptoms and she was doing really well on it)?

Any help you could give would be greatly appreciated.

Dear helen,

Seasson's greetings,

Try to treat patients Homoeopathically. As you expressed here cannot be said as homoeopathic treatment.

Nice informative article. I appreciate your effort. This would help many practitioners and refresh knowledge of others. Keep it up.

we are rocking the medical field with our Homeopathic Specialist))

Dear Sharma ji,

Season's greetings,

The information you provided is good one; however, every patient with hypertension cannot be treated with this drug, unless and until he/she possess other manifestations of the drug, especially, the mental symptoms of drug. The symptoms like you mentioned nausea, vomiting, excessive salivation and diaphoresis, blurred vision, and mental confusion, coldness, craving for icy cold drinks and lemonade and characteristically- cold perspiration on forehead are the symptoms that we find in its drug proving. It clearly implicate that Vert. alb is not homoeopathic to the patient. The drug removed merely only one expression of the disease and not the disease in its entirety. Therefore, the administered drug cannot be said as a homoeopathic remedy to the patient.

DR. S. HARIMANN

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